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Research Study For Major Depressive Disorder in San Diego
(Outpatient & Inpatient)
Eligibility Criteria & A brief description of the study
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Major Depression (Outpatient)
Ages: 18-65
Study Length: 12 Weeks
Visits: 8
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Major Depression (Outpatient)
Ages: 18-65
Study Length: 10 Weeks
Visits: 6
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Major Depression (Monotherapy)
Ages: 18-65
Study Length: 12 Weeks
Visits: 7
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Major Depression (Treatment-Resistant Inpatient)
Ages: 18-65
Study Length: 11 Weeks (5 Inpatient Nights)
Visits: 12
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Synergy Research Centers in Lemon Grove is currently running a clinical research study for patients with major depressive disorder in San Diego. Major depression is one of the most common mental disorders in the United States and can often be misdiagnosed or self-diagnosed. Losing a loved one, your job, or other difficult situations can lead a person to feel this way but these feelings are normal reactions to these events. Those that experience these feelings daily, nearly daily, or for weeks at a time for no reason at all may live with major depression.
What is Major Depression?
Major depression, also known as major depressive disorder (MDD), is a mood disorder characterized by extended periods of sadness, feelings of emptiness, and a loss of interest in once-pleasurable activities. Major depression causes the individual to feel discouraged, hopeless, disinterested, or unmotivated in life in general. When these feelings occur often, last for more than two weeks, and interfere with daily life, it is likely that a depressive episode is occurring.
The severity of depressive symptoms vary from person to person, and may even change from one episode to the next in an individual. Some people who suffer from depression may experience a low mood, while another may feel agitated, angry, or detached. Although everyone may feel depressed at some point in their lives, perhaps following a divorce or the loss of a loved one, MDD is a chronic mental disorder that can set in without any obvious reason. According to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-V), the diagnostic criteria for major depression must involve significant changes in symptoms within 5 or more of the following areas nearly every day within a two-week period.
- Depressed mood most of the day
- Loss of interest/pleasure in most activities
- Changes in appetite, increase or decrease, possibly with marked weight gain or loss
- Changes in sleep habits, excessive sleeping or inability to sleep
- Restless, agitated energy or lethargic energy and slow movements
- Fatigue
- Feelings of worthlessness or inappropriate guilt
-
Decreased concentration or indecisiveness
- Thoughts of death or suicide
In order to meet the criteria for a diagnosis of MDD, the above symptoms must cause significant distress in relationships, work or school performance, and other areas of life. The episodes cannot be not better explained by schizophrenia-spectrum or other psychotic disorders and they must be unrelated to any substance or medical condition. No evidence or history of manic or hypomanic episodes should be present.
How is depression treated?
Many people are able to find relief from their depression symptoms through medication, psychotherapy, or brain stimulation therapies. Unfortunately, not all medications or therapies work for every individual, so it can take some time to discover the right combination and the right dosage that provides the most relief with the fewest side effects. For those whose depression symptoms remain unmanageable even with currently available treatments, continued research is crucial. Depression clinical trials are an important step toward more advanced depression treatments, depression prevention, and a lasting cure.
What to Expect from Depression Clinical Trials?
A clinical depression study begins with a short phone interview with a qualified staff member at Synergy Research Centers. They will ask questions about your battle with major depression, as well as more practical information such as your travel accommodations, age, and medical history. Once approved, you will be asked to come in to our facility in Lemon Grove and begin the study. During the depression trial, study participants will either be given a new depression treatment or a placebo, and you will then communicate how you are feeling with our research team.
What is the Length of Time for a Clinical Depression Study?
The length of time for a depression clinical research trial at Synergy Research Centers can vary depending on the specific study.
What are the Benefits of Participating in a Depression Study?
Participating in a depression study can have many benefits. When you participate in a research study at Synergy Research Centers, you will learn more about the disease and yourself. The team at Synergy is well-versed in the science behind depression, and can answer any and all questions about treatment, symptoms, or more technical questions. Participation in a study will also give you access to modern and new treatments for clinical depression that may be the missing link in your treatment of the illness. Finally, some depression studies offer cash compensation for participating.
Participate in a Depression Clinical Research Study in San Diego
Synergy Research Centers is constantly running clinical research studies for those with major depression disorder in San Diego. If you or someone you know suffers from depression and is seeking treatment, contact Synergy Research Centers today.
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Can You Cure Clinical Depression?
What are the Benefits of Participating in a Depression Study?
Depression is an Illness, Not a Weakness
Additional Resources for Depression
- National Institute of Mental Health
- National Alliance on Mental Illness
- WebMD’s Depression Health Center
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